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Post by 16stonepig on Jul 30, 2012 17:22:17 GMT
I'm just wondering how many people have noticed this:
When I was first going through my med trial, I was prescribed 5mg of methylphenidate. When I went to the chemist I got the Mediket brand. I really didn't notice much of an effect, and so we decided to up my dose. The next time I picked up the prescription, my doctor specifically asked for Ritalin, at 10mg. That increase in dose (and then on to 15mg) was really noticeable - it seemd like it was so much "cleaner" and the effect was much longer lasting.
Now I have been to my GP and been put back on the generic, and I can hardly feel anything working at all! There is maybe 30 minutes of slightly more awareness, but then I just seem to crash and feel really slow and dozy.
I've heard other people say it, but is there really that much difference between brands? Now that my GP is prescribing, I don't feel like I can ask to try different medications or doses - I already get treated like a bloody junky/criminal/lunatic when I go to the pharmacy to pick the pills up, I don't want to feel like that with my doctor too.
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Post by Deleted on Jul 30, 2012 18:49:51 GMT
I'm not on meds now but I did change onto Ritalin at one point and my headache/fluttery-feeling-heart side effects cleared up! I changed by asking my GP after seeing it suggested, so it's always worth a try.
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Post by Deleted on Jul 30, 2012 22:28:17 GMT
I found I got much less anxiety with medikinet compared to ritalin. Ritalin seemed to be so much harsher to me.
John
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Post by nemo on Jul 31, 2012 13:24:03 GMT
Just shows how different formulations effect people differently. I'm the total opposite to John, Medikinet sends my anxiety through the roof. Never tried branded Ritalin (though I'd like to) but Neolabs seems to work ok for me.
There's no harm in bringing it up with your GP though, is there?
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Post by 16stonepig on Jul 31, 2012 13:39:48 GMT
Thanks all. Quite right, there's probably no harm in bringing it up, but I slide into this shame/pessimism state ofmind really easily and I start assuming that the meds are fine, I'm just not trying hard enough.
I also have a very bad habit of saying "Yes, that's fine" to absolutely everything, so if someone suggests a dose and a brand I'll accept it, even if it's not right for me. Everyone else knows better, you see, and I don't want to be a bother...
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Post by nemo on Jul 31, 2012 13:55:06 GMT
:-) I know exactly what you mean. I'm the same. There's nothing to lose by asking though, and potentially much to gain. I'm sure the doctor won't mind if you tell them that Medikinet is not working for you. You're entitled to convey your experiences and have them listened to. Also, there are other generic brands if cost is an issue.
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Post by 16stonepig on Aug 1, 2012 14:42:27 GMT
My god, these are rubbish. It get about 45 minutes of feeling really buzzed, then I just crash and turn into a teary zombie for the 3 hours until my next dose.
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Post by Deleted on Aug 1, 2012 17:49:37 GMT
This one runs and runs and runs (lotsa threads on it).
Unless bootleg drugs have sneaked into the supply chain then a 5mg tab of MPH has 5mg of MPH.
MPH is MPH - it's chemically identical whatever it's in.
Read the ingredients - it's MPH plus a bunch of inert stuff (fillers, glue - stuff like that).
Having said that there is a named brand that I don't like and a generic I don't like.
Theoretically you shouldn't be able to tell the difference and your psychiatrist might laugh at you (yes - that's happened to me).
Is it psychosomatic or is there an actual difference? There really shouldn't be.
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Post by nemo on Aug 1, 2012 20:12:29 GMT
And I suspect it will continue to run as new people with recent diagnoses join the forum. Consequently your comments on the matter are still helpful to peeps while they learn the ropes. It helped me when I asked the exact same question not long after I joined :-)
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Post by Deleted on Aug 1, 2012 22:17:57 GMT
And the search function on here sux otherwise I'd look up the last six times I wrote about it
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Post by nemo on Aug 1, 2012 22:26:30 GMT
Ha! I've started to learn the responses by heart :-) But theyr'e still useful ....
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Post by Lukewaw on Oct 9, 2015 15:44:54 GMT
I second what john says, and I am too stumped by the differences various formulations can have while supplying the same 'active ingredient'. It almost doesn't make sense to me. Brand name Ritalin was pretty stimulating, but less so than adderall. Anxiety was markedly increased but not as much as when I was on adderall. I've also tried generic methylphenidate but forget who produced it, it was also stimulating but felt 'dirtier' than brand Ritalin. Now with the medikinet.... its super smooth, very little anxiety. For me its even smoother with less side effects and anxiety than dexedrine, both spansules and IR
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Post by Deleted on Oct 10, 2015 12:12:36 GMT
Errrrr Ritalin and Adderall are completely different drugs. Adderall is actually a mix of several active ingredients and none of them are methylphenidate.
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Post by Acme on Mar 15, 2017 18:00:35 GMT
Hello, I have been on Medicanet for few months and would like to try Ritalin as Medicanet is not strong enough and doesn't last. I'm looking for the place where I could get some Ritalin. I'm from London. Any advise? Thanks
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Post by marionk on Mar 15, 2017 23:59:42 GMT
They're supposed to be exactly the same and having taken one for several weeks and then switching to the other, and not noticing any difference whatsoever and some time recently to generic without even noticing the lack of brand name let alone any difference in effect, I would say that any brand of IR mph is the same as any other. eta Since writing this I have discovered that actually some brands have slightly different excipients see aadduk.proboards.com/thread/10926/help-needed-medication-brand-uk for more details
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Post by conceptuallycurious on Mar 18, 2017 21:45:43 GMT
There isn't really a difference between the IR pills to my understanding, but there IS a difference between the XR preparations as proportion of IR:XR in each brand.
That said my pharmacy absolutely wouldn't dispense anything but the exact prescription (with a small amount of leniency for typos as the legal situation allows). Even with something like not being able to dispense twice the quantity of 10mg pills because their out of 20mg pills.
I was given Medikinet because it's the only brand with scored pills (or, at least that my CCG prescribes, if there is another) and my paranoid psychiatrist wanted to start me on 2.5mg. Asked for a second opinion and the new psychiatrist is more chilled. That said, I offered to go to a cheaper alternative/generic but he said no. I would only switch if it was for an XR pill.
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Post by RILLZ on Apr 27, 2017 11:19:49 GMT
Actually, the crystal size distribution of MPH affects the bioavailability of the drug and this WILL differ between different generics, though the significance of the difference may or may not be that big. Also, crystal impurities and defects has a significant impact on the properties of a crystal and since no process is ideal, this will also differ (again, significant factor?). So, even though if it is the same active pharmaceutical ingredient in all of the MPH generics, the efficiency of the drug WILL differ but the question is how much. So for those who have different experiences with different generics and so forth, go with what YOU feel is most effective and efficient since everyone have different metabolism and will react different to MPH. PEACE
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Post by Jay on May 24, 2018 8:58:52 GMT
I’m on 50mg double length dose 8 hours ish and it is strong! My body is used to taking it at 7ish and If i forget and take it in school it is like a truck of euphoria hitting me and then full concentration. I’ve never tried Ritalin however if you find these higher doses medicines is in no way a slow placebo pill. You must remember however that you will be an inch shorter using MPH over prolonged use as it suppresses growth slightly.
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Post by Jay on May 24, 2018 9:03:19 GMT
I’m so confused I have quite bad adhd but I’m taking much more than anyone here 50mg medikinet XL? And that doesn’t include filler. Also does anyone else get the feeling that they can’t concentrate when it wears off at all now?
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Post by jp on Jun 5, 2018 10:51:00 GMT
Thanks for resurrecting this thread. Interesting how things change over the years.
For some reason its only young people who are prescribed Ritalin and Medikinet. Why? I don’t know... And perhaps I’m wrong in this assumption? Also kids seem to be often given much higher doses than adults - up to 108mg per day??? This seems incredible since more than 36mg for me is definitley ‘recreational’ shall we say. Also I’m a fully grown, and er... ‘hardened’ adult!
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Post by easilydistracted on Jun 9, 2018 7:57:11 GMT
Possibly because as adults we've accumulated some coping habits that the young have still acquire? Meaning we need less to tip our scales towards 'normality'?
Or that in our pre-dx lost-in-the-wilderness years we've damaged our livers etc sufficiently that the same amount has more effect on us?
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Post by Deleted on Jun 9, 2018 17:53:53 GMT
I'm prescribed a small mountain of elvanse daily and it's never come close to being recreational?
It's taken me years to realise it's doing anything at all.
I think I need better drugs?
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Post by ADDZ on Jun 10, 2018 11:55:45 GMT
Having no history of drug problems or substance misuse , I would like to cut the shit and just use straight Dextroamphetamine. Elvanse changes into it anyway so what’s the logic? Some days I only need to be focused in the AM and some days I only need meds in the PM! I want control over my day thanks you.
Plus god only knows what damage all the extra chemical/biological interactions are taking place from Lisdex-Dex could be causing!
I’m a grown ass man. Just give me the red fucking pill.
Think I’m gonna push him again, ain’t easy though as my Pych is REAL old school, he should of retired in like 2005...he don’t even speak proper English init and mumbles his words
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Post by turnrightnow on Jun 13, 2018 15:42:04 GMT
Nothing really to do with AD-HD Aspergers medication , I was get a lull In the day no energy to do my garden work and got grumpy fed up that I felt like that. Someone suggested magnesium vitamins from health food shop and I find d they really help. They possibly help toward my mental state also.. Ha ha thats why I'm mentioning it here.
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Post by jp on Jun 15, 2018 11:02:58 GMT
I'm prescribed a small mountain of elvanse daily and it's never come close to being recreational? It's taken me years to realise it's doing anything at all. I think I need better drugs? Interesting. Goes to show we are all individuals! On my current dose of Concerta I don’t notice it much although I can see the results - including better sleep (not very rock ‘n’ roll!) But I did notice feeling speedy on each dose increase. And if I take a meds holiday. Only lasts a day though. Once took a double dose of Elvanse by mistake 80 mg or so and was the life of the party... Sadly I only had chickens as company to watch sunrise with :-p I could say so much more but sadly there are legal implications. And I also don’t want to do anything that might make getting meds any harder for us Adders than it already is!
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Post by Andrew11 on Sept 3, 2018 1:46:19 GMT
Agreed! The chemical composition of each brand of ADHA medications affects us all differently. Mainly, most are methylphenidate hydrochloride. so if they're the same why do they affect us differently? Well, there is different chemical composition that produces methylphenidate hydrochloride. Some mixtures are fully metabolised by the body and some are not. Essentially still having the same effect. This is most likely what is affecting us on an individuals level.
Now onto Medikinet XL & Medikinet IR. Firstly, I would like to state that my NHS consultant psychiatrist is one of the loveliest people I have ever met and an outstanding representative of our national health service. The service I have received from my diagnosis 5 months ago at 28 years of age, was second to none. I am currently on 50mg of Medikinet XL (extended release) & 20mg Medikinet IR (immediate release) top up. A maximum daily dosage of 70mg of methylphenidate hydrochloride. If I don't feel like I need my topup I don't take it. Same goes for my extended release pills, Some days like the weekends I tweak my intake based on what I need it for and take the immediate release pills. Medikinet works very well for me even if I am drinking, it's more enjoyable; not falling all over the place; alert and the life of the party. But this due to these medications being stimulants and stimulants have side affects. I have purchased a fabulous little heart rate monitor from Amazon for £12 and regularly check my readings to make sure everything is in order. I would recommend you all do the same.
Peace & Love
A
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Post by Andrew11 on Sept 3, 2018 1:48:07 GMT
Agreed! The chemical composition of each brand of ADHA medications affects us all differently. Mainly, most are methylphenidate hydrochloride. so if they're the same why do they affect us differently? Well, there is different chemical composition that produces methylphenidate hydrochloride. some mixtures are fully metabolised by the body and some are not. Essentially still having the same effect. This is most likely what is affecting us on an individuals level.
Now onto Medikinet XL & Medikinet IR. Firstly, I would like to state that my NHS consultant psychiatrist is one of the loveliest people I have ever met and an outstanding representative of our national health service. The service I have received from my diagnosis 5 months ago at 28 years of age, was second to none. I am currently on 50mg of Medikinet XL (extended release) & 20mg Medikinet IR (immediate release) top up. A maximum daily dosage of 70mg of methylphenidate hydrochloride. If I don't feel like I need my topup I don't take it. Same goes for my extended release pills, Some days like the weekends I tweak my intake based on what I need it for and take the immediate release pills. Medikinet works very well for me even if I am drinking, it's more enjoyable; not falling all over the place; alert and the life of the party. But this due to these medications being stimulants and stimulants have side affects. I have purchased a fabulous little heart rate monitor from Amazon for £12 and regularly check my readings to make sure everything is in order. I would recommend you all do the same.
Peace & Love
A
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slangking
Member's not posted much yet
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Post by slangking on Sept 20, 2018 16:28:55 GMT
I'm taking Medikinet 15mg, it only last for about an hour and then I'm back to normal. Do I need to up the dosage or is this just how it is?
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Post by Liam 77 on Sept 22, 2018 5:48:07 GMT
I'm just wondering how many people have noticed this: When I was first going through my med trial, I was prescribed 5mg of methylphenidate. When I went to the chemist I got the Mediket brand. I really didn't notice much of an effect, and so we decided to up my dose. The next time I picked up the prescription, my doctor specifically asked for Ritalin, at 10mg. That increase in dose (and then on to 15mg) was really noticeable - it seemd like it was so much "cleaner" and the effect was much longer lasting. Now I have been to my GP and been put back on the generic, and I can hardly feel anything working at all! There is maybe 30 minutes of slightly more awareness, but then I just seem to crash and feel really slow and dozy. I've heard other people say it, but is there really that much difference between brands? Now that my GP is prescribing, I don't feel like I can ask to try different medications or doses - I already get treated like a bloody junky/criminal/lunatic when I go to the pharmacy to pick the pills up, I don't want to feel like that with my doctor too.
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Post by Liam 77 on Sept 22, 2018 6:11:18 GMT
The two main factors that I have seen over the years in and out of treatment for adhd and addiction that create the symptoms you have spoken about are as mentioned brand vs generic but also tolerance. There are many people who have some unwanted side effects from one brand of many medication treatments, especially with both mental health and pain meds. I had to fight really hard to go back on lyrica (pregabalin) for my anxiety when given another brand called "doctor ready" as it made being able to do simple tasks really difficult as my anxiety actually increased and I felt nauseous. I spent weeks trying to get the doctors to change it back, it came down to them saving money of course which I said I'd make up myself to get my life back, as I am quite sure the doctor would if faced with the same situation. I have just changed from ritalin to medikinet again, I have had them both a couple of times now, apart from small differences in how long they start to work and last, I think they are very much the same, what has changed is my tolerance, when I started taking methylphenidate, 5mg three times daily was a sufficient dose but 6 months later I am taking 15mg three times daily, that seems to be a good dose for me and I haven't needed an increase in a while, fingers crossed! I hope this was helpful
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