From my own investigations, many people have similar reactions to different brands - despite the "they all contain the same" argument.
I found 2 original pills in my overnight bag last week - so decided to test it out. I had been feeling my recently normal lethargic self, having taken the new pills in the morning.
Then, instead of the new ones, I replaced the next one with one of the originals I had just found.
Within 30 minutes I was feeling cheerful, awake, alert - I remembered a bunch of jobs I needed to do and had recently been putting off (for about 3 weeks), and just did them without a second thought - I chatted to the neighbours and was back to feeling "human".
When it ran out I then took the new ones again - within 30 minutes I wanted to curl up and go to sleep, I started to feel grumpy for no reason and was back to this new version of me.
I tried the experiment again at the weekend, and had the exact same results.
I am an analyst by trade, and work for the health service, so understand the placebo effect - but this was clearly a physical difference, and a massive one.
The pills react very differently in my system, despite the "they contain the exact same ingredients" theory. Something is different, and whatever it is, I do not react well to it at all.
I really need some help from my fellow ADHD UK members.
This is a real long shot but you never know!
So, I was taking a med called Tranquilyn for the last year, and personally I had a great reaction to it. I was alert, coordinated, a real "go-getter" and very organised.
Then my pharmacist got a different brand, by a company called Neolabs. Suddenly I was asleep most of the day, walking in a dream. I thought I had something wrong with me, or was over worked, and it wasn't until a few weeks later that I realised that as soon as the meds wore off I became less tired. I convinced the pharmacist to specify the original brand, which he did, and the next day I was right back to bouncy-get-stuff-done me.
Then - two months ago he announced he couldnt get the brand anymore. The wholesaler who he bought from wasn't stocking it, and was stocking a different brand - this time by someone called Lexon. Worryingly their meds arrived with their branding stickers over the actual medication pill packet back, which was odd (you can peel it off and see the original). Taking them makes me feel semi tired, and semi not with it. Its like not being on them. For the last two months things have gone downhill for me. I can no longer concentrate at work, Im forgetting stuff, im procrastinating, im feeling grumpy and argumentative... basically "me without the meds". Its affecting my personal and work life, Im starting to withdraw into myself, and is causing me to become depressed.
So... my pharmacist suggested this - if I could find a wholesaler in the UK who stocks "my" brand, he will order them from there for me from now on! But I have no idea where to find a wholesaler, or at the moment what the brand is even called ! (Cos I forgot to ask him, then procrastinated, then chickened out of going back to ask him the name, then ran out of time, and now its friday at 9pm and I finally made an account and wrote this lol). I have a bit of one of my old packets to help me track it down
So... does anyone use a brand of Methylpenidate Hydrochloride called "Tranquilyn" that comes in a white box with the mg in a blue box with rounded corners - possibly made by someone called Gensis, or Genysis, or possibly not made by them? And if it sounds familiar, would you be possibly willing to share with me where in the UK you order them, so I could try and call your pharmacy and ask them the wholesalers name, so I could give it to my pharmacy.. Or I could just give my pharmacist your pharmacists number and he could call them "pharmo to pharmo" so to speak!
As I say - this is a long shot, and sorry for the novel...
If you do use this and understandably dont want to reveal your whereabouts to a stranger on the internet, but could give me a clue to the town or area, so I could call around the chemists there - even that would give me some hope.
Many thanks for reading. Your time is appreciated.