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Post by roland on Oct 21, 2008 17:05:15 GMT
Information about dosage, side effects, warnings and pharmacological information: 1. UK Information: None available. Adderall appears only to be available (with difficulty) off-licence: 2. USA Informationwww.rxlist.com/adderall-drug.htm
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jeff
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Post by jeff on Jul 26, 2009 18:17:27 GMT
What does "off-licence" mean?
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Deleted
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Post by Deleted on Jul 26, 2009 18:37:20 GMT
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jeff
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Post by jeff on Jul 28, 2009 14:33:12 GMT
Thank you.
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Post by pinkbeauty on Aug 4, 2009 20:38:05 GMT
Just got round to reading this properly. I still don't really get it. The article talks about drug licences as though they're needed for the drug to be used. But, apparently, in another thread, no medication for ADHD is licenced in this country?? Hi Jeff In the UK most medications in general are licensed for adults but can be prescribed for children if the Dr believes it is necessary. All ADHD medications, however, are the other way around and licensed for children, but if your Dr is agreeable can prescribe for adults. It just makes it more difficult for GPs to prescribe and some don't like prescribing 'off licence'. Times are changing however, and with NICE now recognising Adults with ADHD and things moving (allbeit slowly) for us generally, hopefully this will change soon. Hope this helps. PB
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jeff
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Post by jeff on Aug 4, 2009 22:28:48 GMT
Well, I don't really get the point of licencing laws then! If doctors just prescribe it anyway! Obviously as much as I'm for proper medication available for people with ADD, licencing is there for a reason, isn't it?
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Post by pinkbeauty on Aug 5, 2009 0:15:17 GMT
Well, I don't really get the point of licencing laws then! If doctors just prescribe it anyway! Obviously as much as I'm for proper medication available for people with ADD, licencing is there for a reason, isn't it? Its just a guide. Some Dr's wouldn't prescribe it for that very reason. But also, look at it the other way around, most drugs are licensed for adults, so if a child is ill and needs it shouldn't they be able to get it? The medical profession haven't long acknowledged that ADHD exists in Adults, hence the current licensing, it wouldn't be needed for adults if it didn't exist. But it does, so hopefully will be changed soon and licensed for both adults and children which should make getting hold of it a lot easier for those who need it. PB
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jeff
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Post by jeff on Aug 7, 2009 10:31:43 GMT
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Post by Deleted on Aug 7, 2009 12:50:22 GMT
The irony is, that Adderall was developed by a British company, Shire pharmaceuticals. -but is not available in the UK.
the reason for this is, that to obtain a license, the company has to demonstrate that the new medicine is both safe & effective.
this requires a lot of trials and costs tens of millions of pounds. so the company has to ask itself, which country has the biggest market?
and that's the reason that the US gets all the new drugs first.
so these are the facts, Adderall works, it is very safe, and it has been given out in millions of prescriptions throughout the US and around the world.
so why can't we have it here?
because to obtain a license in the UK, Shire can't just submit the trials they have already done in the US, for review by british scientists. because of a political decision by the UK government to protect the EU pharmaceutical testing industry, Shire would have to re-do all the same trials over again. at a cost of further millions
so we're left in a situation where a British company invents a medicine, that everyone knows works, everyone knows is safe and is taken by millions, but nobody in britain is allowed to have!...
Absurd!
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Post by Deleted on Aug 7, 2009 14:21:03 GMT
As Matt says - it's a financial decision.
And because the NHS very nearly refuses to diagnose ADHD there is very little demand for ADHD drugs thus keeping the market small.
So it's not just Shire's (or the other pharma companies) fault. Shire (et al) would love to supply more drugs and having Europe on board would improve their economy of scale for enhanced profitability.
But Europe isn't diagnosing much.
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Post by Deleted on Aug 7, 2009 14:55:20 GMT
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jeff
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Post by jeff on Aug 8, 2009 16:23:16 GMT
The irony is, that Adderall was developed by a British company, Shire pharmaceuticals. -but is not available in the UK. the reason for this is, that to obtain a license, the company has to demonstrate that the new medicine is both safe & effective. this requires a lot of trials and costs tens of millions of pounds. so the company has to ask itself, which country has the biggest market? and that's the reason that the US gets all the new drugs first. so these are the facts, Adderall works, it is very safe, and it has been given out in millions of prescriptions throughout the US and around the world. so why can't we have it here? because to obtain a license in the UK, Shire can't just submit the trials they have already done in the US, for review by british scientists. because of a political decision by the UK government to protect the EU pharmaceutical testing industry, Shire would have to re-do all the same trials over again. at a cost of further millions so we're left in a situation where a British company invents a medicine, that everyone knows works, everyone knows is safe and is taken by millions, but nobody in britain is allowed to have!... Absurd! Oh my god. That's insane. So, is Adderall licensed for children? You'd think if a set of drugs were given the all clear to be prescribed to children, it wouldn't be that much more difficult to give them the all clear to be prescribed to adults!
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Deleted
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Post by Deleted on Aug 8, 2009 19:35:16 GMT
Adderall's not licensed for Adults or Children in the UK. Shire has 3 very good ADHD drugs available in the U.S. -Adderall XR (mixed amphetamine salts) -Vyvanse (an extended release amphetamine preparation) -Daytrana (a transdermal methylphenidate patch) - which is like the ADHD version of a nicotine patch for smokers, none of which are available in the UK. Shire are currently conducting 2 trials for Vyvanse i believe one is in the UK, at either bristol or The Maudsley. they have recently withdrawn a european license application for Daytrana. www.news-medical.net/news/2009/03/16/46978.aspxas far as i know, they have no plans to apply for a license for Adderall.
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jeff
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Post by jeff on Aug 8, 2009 22:36:04 GMT
@ your knowledge! Thanks! So which ADHD drugs are licensed for children in the UK?
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Post by Deleted on Oct 26, 2009 19:39:51 GMT
It is actually even worse than has been explained above. Adderall is now out of Shire's patent protection, so Shire no longer has a protected market for it. Due to recent EU legislation because Adderall is comprised of four seperate chemicals, each chemical would need to be independently tested! So not a chance of a business case for licensing.
The unique effect that Adderall has is based on it having four different amphetamine salts in it (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate (dexedrine); dextroamphetamine sulfateactually). The dextroamphetamine is more potent, but the (levo)amphetamine has a greater physiological effect (e.g. cardiovascular), a quicker and longer clinical effect and impacts nor-adrenaline for a better motivational effect for many than Ritalin or Dexedrine/Vyvance. So sadly a unique medication used by the majority of Americans will never be available in the UK.
A real shame. You can get it privately for a cost of around £8/pill, for many they need 2 pills a days so that's an annual cost of around £7,000 including 12 consults. Not cheap.
regards
Andrew
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Post by Deleted on Aug 14, 2012 18:41:29 GMT
I had my physciatrist prescribing dexedrine for years at 100mg a day,when i approached her in 2006/7 and asked could i change dex to adderall.She did look into it thorugh,going through the bnf with a lot to read,phoning drug companys,ect ect and the outcome in manchester was there is no licence at all for the script off adderrall in the uk.And she was a great doc and tried her best but nope...you see the odd thing/hear the odd thing but nothing to hold any adderall storys down for the uk prescriptions,buy off the web...no way,poison.
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flembot
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Post by flembot on Jul 11, 2014 13:01:40 GMT
It is actually even worse than has been explained above. Adderall is now out of Shire's patent protection, so Shire no longer has a protected market for it. Due to recent EU legislation because Adderall is comprised of four seperate chemicals, each chemical would need to be independently tested! So not a chance of a business case for licensing. The unique effect that Adderall has is based on it having four different amphetamine salts in it (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate (dexedrine); dextroamphetamine sulfateactually). The dextroamphetamine is more potent, but the (levo)amphetamine has a greater physiological effect (e.g. cardiovascular), a quicker and longer clinical effect and impacts nor-adrenaline for a better motivational effect for many than Ritalin or Dexedrine/Vyvance. So sadly a unique medication used by the majority of Americans will never be available in the UK. A real shame. You can get it privately for a cost of around £8/pill, for many they need 2 pills a days so that's an annual cost of around £7,000 including 12 consults. Not cheap. regards Andrew Hi Andrew, its good to know these things. Would you be aware as to why we do not have the dexamphetamine spansules/dexamphetamine extended release in the UK? I understand we have had Elvanse since August 2013, however, it was effective for innatention and everything else for a few hours (30mg dose) however, it lost effectiveness around 1pm (if taken at 08:00AM) and after seven hours (08:00AM +7hrs) I would be experiencing extreme stomach pain which would extend right through to the lower back which manifested as back pain which meant that I could not sit comfortably or lie comfortably in bed trying to ride it out. The strong pain from this stressed me out a lot and was unbearable, it felt like acid was buring through my stomach. However, I have to say, Andrews Liver Salts were a god send! It was the only thing that provided me with relief from the stomach pain, rennies or gaviscon didn't do a thing, probably because they did contain sodium bicarbonate.... Anyways, I had tried Elvanse for a reasonable period of time to see if this side effect would dissapate, however, it didn't, ever, and the stress (deadlines looming and stomach pain every late afternoon and into the evening as a result of the Elvanse) was gradually getting to much and prevented me from getting things done also. This is why I ask about the Dexedrine Extended release spansules that are available in the USA but not over here in the UK.... It doesn't make any sense considering it is the same drug only with a different release mechanism. I am curious to know why this might be. Thanks Andrew
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billywhizz
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Post by billywhizz on Jul 3, 2015 1:00:01 GMT
As someone who has been luck enough to try Adderall I wish it was available over here. It was amazing for me, no MPH comes close and I am not allowed on Dex yet. A months worth is $80, but my mate is no longer talking to me, so no chance of anymore
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