Post by Steve Lukito on Apr 22, 2015 18:40:01 GMT
Neurocognitive and Functional MRI Correlates of Attention Deficit Hyperactivity Symptoms in Autism Spectrum Disorders (ASD)
Hello, my name is Steve and I am a PhD researcher at King's College London. I am running the study below which I hope will interest you. Below are some of the frequently asked questions (FAQs) about our study. If you have further questions or want to take part, please email me at snap@kcl.ac.uk or ring 02078480469 and talk to me.
What is this project and its objectives?
The symptoms of Attention Deficit and Hyperactivity (ADHD) are present in increased rates in Autism Spectrum Disorder (ASD), which suggests a relationship between the two conditions. However, the mechanism underlies the overlap of the two conditions are still largely unknown. We compare the ADHD symptoms and brain functions in ASD against those in ADHD alone. We will look for similarities and differences in brain functions that might explain these symptoms. By doing this study we hope to improve our understanding about ASD, ADHD and their co-occurrence. This study received ethical approval from the NHS REC (Ref 13/LO/0373).
What does it involve?
This study involves some questionnaires, mind puzzles, computerized “neurobehavioural” tasks and a brain scan (MRI). The study is done in two sessions of 2.5-3 hours each, which can be completed in one day or more if preferred. We can visit you at home for part of the study although you will need to travel to our research site at Denmark Hill for the MRI scan. You will be given £50 for your time and lunch and travel expenses will be reimbursed.
Can I take part?
We invite male participants aged 21-26 years with diagnosis of ADHD (with or without additional diagnosis of ASD). You cannot take part if you have learning disability, substance abuse/dependence, current epilepsy and some psychiatric illnesses (please ring and discuss). If you are currently taking stimulant-based medication, you will need to stop taking them for 48 hours before the research day.
What are the design/methods of the project?
In this study we compare four groups of participants: (1) participants with ASD alone, (2) participants with ADHD alone, (3) participants with dual diagnosis of ASD and ADHD, and finally (4) a control group in several neurobehavioural tasks and structural and functional MRI scans. Our main outcome measures are brain structures and activations during fMRI. We also compare the groups' results on all neurobehavioural tasks. We also take into account people's mood and general learning and thinking ability when we analyse our data.
Who are involved in this research?
Professor Emily Simonoff (Principal Investigator)
Professor Katya Rubia (Principal Investigator)
Mr Steve Lukito (PhD Student)
Who funds this study and what organizations are involved?
We are part-funded by Autism Speaks and Mr Steve Lukito is funded by the Medical Research Council (MRC)-IoP studentship. We are based at the Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience at King’s College London. We collaborate with South London and Maudsley NHS Trust for this study.
Is the study still running?
We have started since 12/2013 and will complete all research including data analyses by 09/2016. We hope to finish all data collection by 03/2016.
Thank you for reading this message. I look forward to hearing from you!
Hello, my name is Steve and I am a PhD researcher at King's College London. I am running the study below which I hope will interest you. Below are some of the frequently asked questions (FAQs) about our study. If you have further questions or want to take part, please email me at snap@kcl.ac.uk or ring 02078480469 and talk to me.
What is this project and its objectives?
The symptoms of Attention Deficit and Hyperactivity (ADHD) are present in increased rates in Autism Spectrum Disorder (ASD), which suggests a relationship between the two conditions. However, the mechanism underlies the overlap of the two conditions are still largely unknown. We compare the ADHD symptoms and brain functions in ASD against those in ADHD alone. We will look for similarities and differences in brain functions that might explain these symptoms. By doing this study we hope to improve our understanding about ASD, ADHD and their co-occurrence. This study received ethical approval from the NHS REC (Ref 13/LO/0373).
What does it involve?
This study involves some questionnaires, mind puzzles, computerized “neurobehavioural” tasks and a brain scan (MRI). The study is done in two sessions of 2.5-3 hours each, which can be completed in one day or more if preferred. We can visit you at home for part of the study although you will need to travel to our research site at Denmark Hill for the MRI scan. You will be given £50 for your time and lunch and travel expenses will be reimbursed.
Can I take part?
We invite male participants aged 21-26 years with diagnosis of ADHD (with or without additional diagnosis of ASD). You cannot take part if you have learning disability, substance abuse/dependence, current epilepsy and some psychiatric illnesses (please ring and discuss). If you are currently taking stimulant-based medication, you will need to stop taking them for 48 hours before the research day.
What are the design/methods of the project?
In this study we compare four groups of participants: (1) participants with ASD alone, (2) participants with ADHD alone, (3) participants with dual diagnosis of ASD and ADHD, and finally (4) a control group in several neurobehavioural tasks and structural and functional MRI scans. Our main outcome measures are brain structures and activations during fMRI. We also compare the groups' results on all neurobehavioural tasks. We also take into account people's mood and general learning and thinking ability when we analyse our data.
Who are involved in this research?
Professor Emily Simonoff (Principal Investigator)
Professor Katya Rubia (Principal Investigator)
Mr Steve Lukito (PhD Student)
Who funds this study and what organizations are involved?
We are part-funded by Autism Speaks and Mr Steve Lukito is funded by the Medical Research Council (MRC)-IoP studentship. We are based at the Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience at King’s College London. We collaborate with South London and Maudsley NHS Trust for this study.
Is the study still running?
We have started since 12/2013 and will complete all research including data analyses by 09/2016. We hope to finish all data collection by 03/2016.
Thank you for reading this message. I look forward to hearing from you!