Post by andy12345 on Aug 22, 2009 13:47:54 GMT
I find this quite interesting.
Study results whilst doing calculations (maths etc).......
There is no difference when not calculating.
Non-ADHD person + methyphenidate (Ritalin brand) = no difference of glucose use versus un-medicated...er average person (aka normal :/ ).
However..
ADHD person + (methyphenidate)brand Ritalin = less glucose use in brain versus un-medicated ADHD
So, here is clear evidence for those who have not seen it, that
a person with ADHD will clearly use less glucose when medicated.
Now, this also means that they will use more glucose whilst unmedicated and "trying" to work on things...
What is not clear is how much glucose is used up per unit of time whilst calculating or doing "activating" tasks compared to non-adhd people.
Does this mean that adders need more constant complex carbs. to help them a little bit, particularly even little but often..
Does that help by a small percentage?
Anyone know about this?
www.ncbi.nlm.nih.gov/pubmed/18414677?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_PMC&linkpos=3&log$=citedinpmcarticles&logdbfrom=pubmed
Below, is a small QUOTE from the extract on the website.
[Compared to placebo methylphenidate significantly reduced the amount of glucose utilized by the brain when performing the cognitive task but methylphenidate did not affect brain metabolism when given without cognitive stimulation. Whole brain metabolism when the cognitive task was given with placebo increased 21% whereas with methylphenidate it increased 11% (50% less). This reflected both a decrease in magnitude of activation and in the regions activated by the task. Methylphenidate's reduction of the metabolic increases in regions from the default network (implicated in mind-wandering) was associated with improvement in performance only in subjects who activated these regions when the cognitive task was given with placebo.
Study results whilst doing calculations (maths etc).......
There is no difference when not calculating.
Non-ADHD person + methyphenidate (Ritalin brand) = no difference of glucose use versus un-medicated...er average person (aka normal :/ ).
However..
ADHD person + (methyphenidate)brand Ritalin = less glucose use in brain versus un-medicated ADHD
So, here is clear evidence for those who have not seen it, that
a person with ADHD will clearly use less glucose when medicated.
Now, this also means that they will use more glucose whilst unmedicated and "trying" to work on things...
What is not clear is how much glucose is used up per unit of time whilst calculating or doing "activating" tasks compared to non-adhd people.
Does this mean that adders need more constant complex carbs. to help them a little bit, particularly even little but often..
Does that help by a small percentage?
Anyone know about this?
www.ncbi.nlm.nih.gov/pubmed/18414677?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_PMC&linkpos=3&log$=citedinpmcarticles&logdbfrom=pubmed
Below, is a small QUOTE from the extract on the website.
[Compared to placebo methylphenidate significantly reduced the amount of glucose utilized by the brain when performing the cognitive task but methylphenidate did not affect brain metabolism when given without cognitive stimulation. Whole brain metabolism when the cognitive task was given with placebo increased 21% whereas with methylphenidate it increased 11% (50% less). This reflected both a decrease in magnitude of activation and in the regions activated by the task. Methylphenidate's reduction of the metabolic increases in regions from the default network (implicated in mind-wandering) was associated with improvement in performance only in subjects who activated these regions when the cognitive task was given with placebo.