Post by roland on Oct 1, 2008 22:04:40 GMT
Here are details of another research project that ihas already begun, and is expected to finish in 2010:
Title:
A whole-genome linkage study of Attention Deficit Hyperactivity Disorder (ADHD) with antisocial behaviour as a covariate
Research Summary:
ADHD is the commonest reason for children attending child mental health clinics in the UK and has long term adverse consequences in adult life. Little is understood about how ADHD develops although we know that genes contribute with environmental factors. Understanding more about the causes of ADHD will inform us on better methods of treatment and providing help. So far researchers have examined whether genes that they have chosen might be involved in the development of ADHD. There is however a need to examine all genes, not just genes we think might be involved, to gain new insights into the biology of ADHD. There is also a need for genetic studies to take environmental adversity into account and this has not yet been undertaken for the type of ADHD genetic study we propose. Finally ADHD can present in different ways. Around half of those affected show serious antisocial behaviours (e.g. seriously injuring others). This study aims to identify genes that increase susceptibility for ADHD, have an effect on serious antisocial behaviour in ADHD and where the effects depend on whether or not a child is exposed to an adverse early environment.
While centres throughout England and Wales are taking part in the study, it's actually being managed by the following:
University Hospital of Wales
Heath Park
Cardiff, CF14 4XW
Title:
A whole-genome linkage study of Attention Deficit Hyperactivity Disorder (ADHD) with antisocial behaviour as a covariate
Research Summary:
ADHD is the commonest reason for children attending child mental health clinics in the UK and has long term adverse consequences in adult life. Little is understood about how ADHD develops although we know that genes contribute with environmental factors. Understanding more about the causes of ADHD will inform us on better methods of treatment and providing help. So far researchers have examined whether genes that they have chosen might be involved in the development of ADHD. There is however a need to examine all genes, not just genes we think might be involved, to gain new insights into the biology of ADHD. There is also a need for genetic studies to take environmental adversity into account and this has not yet been undertaken for the type of ADHD genetic study we propose. Finally ADHD can present in different ways. Around half of those affected show serious antisocial behaviours (e.g. seriously injuring others). This study aims to identify genes that increase susceptibility for ADHD, have an effect on serious antisocial behaviour in ADHD and where the effects depend on whether or not a child is exposed to an adverse early environment.
While centres throughout England and Wales are taking part in the study, it's actually being managed by the following:
University Hospital of Wales
Heath Park
Cardiff, CF14 4XW