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Post by carly31 on Jul 20, 2014 11:48:03 GMT
Has anyone been given diazepam for anxiety? I don't take any ADHD meds at the mo but I'm really anxious.
GP gave me some diazepam but I feel like I've taken a class A drug. Trippy vision, bizzare trippy thoughts, itchy skin, increased restlessness, nightmares and one hell of a come down!
Obviously this drug isn't for me, but just wondering if anyone else has had this adverse effect and whether it's to do with ADHD?
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Post by twix on Jul 20, 2014 12:02:31 GMT
Could be adhd.
I know that psudoephedrine (sinus medication) wakes normal people up and puts me to sleep.
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Post by contrarymary on Jul 20, 2014 12:27:54 GMT
Has anyone been given diazepam for anxiety? I don't take any ADHD meds at the mo but I'm really anxious. GP gave me some diazepam but I feel like I've taken a class A drug. Trippy vision, bizzare trippy thoughts, itchy skin, increased restlessness, nightmares and one hell of a come down! Obviously this drug isn't for me, but just wondering if anyone else has had this adverse effect and whether it's to do with ADHD? Hi carly31i given diazepam for muscle spasms caused by a neuro condition, rather than for anxiety. i was on a very high dose for some years. i found that it made me hyper and restless, gave me very vivid dreams rather than nightmares, but then i v rarely have nightmares. on diazepam i did actually say absolutely everything i was thinking with absolutely zero ability to hold it in anytime, no matter where or with whom. it basically is like adhd taken to infinity and beyond. plus the body adjusts really quickly, so to achieve the same affect the dose needs to be increased over time. this can lead to a rebound of symptoms every time the dose is adjusted, and indeed can lead to far more symptoms than you started with. it is really really difficult to come off after a short time - far worse than heroin - and massively impairs the working memory. there are loads of studies that say how benzodiazepines cause both addiction and brain shrinkage. personally i can almost feel the damage that has been done to my brain and thinking ability by years of taking prescribed diazepam. if i had known then what i know now.... i would honestly caution everyone not to take it unless it was to save their life. the backwards reaction you describe is called a paradoxical effect and can happen to anyone with any drug, but is known to happen to some people with adhd who take benzodiazepines.
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Post by scatterbrain on Jul 20, 2014 12:38:30 GMT
OK, I'm not medically qualified in any way but isn't Diazepam a bad choice for anyone with ADHD since it can impair memory and attention?
I was on morphine patches taken every 3 days. It not only eased the pain but where it makes normal people sleepy, on patch day I would be wide awake and busy for around 20 hours before the drowsiness set in. Don't know if it was down to ADHD or not but I did get a lot done in those days.
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Post by scatterbrain on Jul 20, 2014 12:41:23 GMT
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Post by carly31 on Jul 20, 2014 13:07:15 GMT
I don't think I'll be getting addicted to them any time soon. Actually, the itching I'm getting resembles the itching I get from coffee. I think I'm just quite sensitive to chemicals in my body. They're only PRN as I have exams next week and I just want to complete them this time around- uni has already taken me and extra year and half- I just want it out of the way!
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Post by contrarymary on Jul 20, 2014 19:45:47 GMT
i meant addiction as a physical thing - the brain/body quickly adjusts and has some sort of dysfunction without it - rather than a psychological addiction. (tho actually the interplay of the two can be pretty complicated, as i discovered when stopping smoking and the way my brain went haywire without nicotine... but that's another story) v best of luck with the exams carly31
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Post by leftbehind1 on Jul 21, 2014 0:16:24 GMT
Diazepam seems to me like a very bad idea yea it's good for sleep but not exactly a great thing to be walking around the day with plus they can be pretty addictive. I've taking my fair share of them but that was for sleep and the next day Ur lethargic and not all together there.
That seems like a ridiculous medication to dish out for daily anxiety has he ever heard of ssri or beta blockers
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Post by carly31 on Jul 21, 2014 2:59:20 GMT
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Post by carly31 on Jul 21, 2014 3:31:31 GMT
Diazepam seems to me like a very bad idea yea it's good for sleep but not exactly a great thing to be walking around the day with plus they can be pretty addictive. I've taking my fair share of them but that was for sleep and the next day Ur lethargic and not all together there. That seems like a ridiculous medication to dish out for daily anxiety has he ever heard of ssri or beta blockers I'm sure she has, but I don't have daily anxiety and ssri's don't agree with me either.It doesn't help me sleep it makes me hyper!! :-D
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Post by leftbehind1 on Jul 21, 2014 4:07:01 GMT
Yea that very strange could u be allergic . I don't know I find when I took diazepam I would be drowsy but fighting to stay awake would make me irritable. it myt numb down ur ability to normally control adhd and ur subsequently more hyper but hey just my opinion
I wouldn't like to be on them things daily and I used to abuse them in my teens And yea the itchy skin and restlessness and random thoughts and vision disturbances sounds either like an allergic reaction or a slight Overdose but that's just my opinion what mg are u on and how many a day?
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Post by carly31 on Jul 21, 2014 9:37:11 GMT
2mg but can take up to 6mg a day. They're not for taking daily. Just when I need them. The idea was to take them to help me sleep as I had zopiclone a few months ago but it's very addictive. Works a treat and no side effects - guess that's why it's addictive! I tried 1mg of diazepam last night and still same effect. I guess I should just go back to docs, she knows best! :-D
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andres
Member's posted somewhat
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Post by andres on Jul 21, 2014 13:38:08 GMT
Definitely tell your doctor, very unusual to be stimulated from benzodiazepines. Whenever I've had them, they've always calmed me right down. By the way, diazepam is just as addictive as zopiclone.
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andres
Member's posted somewhat
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Post by andres on Jul 21, 2014 13:47:56 GMT
OK, I'm not medically qualified in any way but isn't Diazepam a bad choice for anyone with ADHD since it can impair memory and attention? I was on morphine patches taken every 3 days. It not only eased the pain but where it makes normal people sleepy, on patch day I would be wide awake and busy for around 20 hours before the drowsiness set in. Don't know if it was down to ADHD or not but I did get a lot done in those days. Morphine will make most people stimulated if the dose is high enough, maybe on patch day there was more in your system? Sadly I'm an expert on these kinds of drugs through years of self medicating as a yoof.
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Post by carly31 on Jul 21, 2014 14:23:44 GMT
Definitely tell your doctor, very unusual to be stimulated from benzodiazepines. Whenever I've had them, they've always calmed me right down. By the way, diazepam is just as addictive as zopiclone. Hence why it's PRN medication like zopiclone.
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Post by carly31 on Jul 21, 2014 14:41:01 GMT
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andres
Member's posted somewhat
Posts: 52
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Post by andres on Jul 21, 2014 14:56:56 GMT
Link just comes up with a log in for Medscape. What is it?
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Post by carly31 on Jul 21, 2014 21:40:00 GMT
Abstract
Benzodiazepines are frequently administered to patients to induce sedation. Paradoxical reactions to benzodiazepines, characterized by increased talkativeness, emotional release, excitement, and excessive movement, are relatively uncommon and occur in less than 1% of patients. The exact mechanism of paradoxical reactions remains unclear. Most cases are idiosyncratic; however, some evidence suggests that these reactions may occur secondary to a genetic link, history of alcohol abuse, or psychological disturbances. This review evaluates the numerous cases of paradoxical reactions to benzodiazepines in adult and pediatric patients that have been reported in the biomedical literature. It also explores the advantages and disadvantages of the various available treatment options.
Introduction
Benzodiazepines are used primarily in the treatment of generalized anxiety and panic disorders, as sedative hypnotics, muscle relaxants, and anticonvulsants. These agents exert their pharmacologic action by binding to benzodiazepine-γ-aminobutyric acid (GABA)-type A-chloride receptors in the central nervous system.[1] This action results in increased inhibitory action of GABA, producing a state of relaxation and inducing anterograde amnesia.
Benzodiazepines commonly are given alone or in combination with anesthetics to induce sedation. Unfortunately, some patients experience paradoxical reactions to these agents.[1] These reactions are characterized by increased talkativeness, emotional release, excitement, excessive movement, and even hostility and rage. The pathophysiologic mechanisms underlying these reactions are unclear; however, several predisposing risk factors have been identified. These include young and advanced age, genetic predisposition, alcoholism, and psychiatric and/or personality disorders. Children and elderly patients may be more predisposed than other patients to paradoxical reactions with benzodiazepines. It has been theorized that these subgroups of patients have alterations in the pharmacodynamic response to benzodiazepines; however, the exact differences have not been specifically characterized in the literature.[2] Some patients may have a genetic variability in the benzodiazepine-GABA-chloride receptor that results in an abnormal pharmacodynamic response.[3] Multiple allelic forms of genetically determined benzodiazepine receptors exist, resulting in differing affinity for benzodiazepines among patients.
Patients who are alcoholic may be at increased risk of adverse reactions from benzodiazepines due to an alteration of the neuroregulatory mechanisms of the brain.[4] Alcoholics are believed to have decreased synthesis and functioning of GABA, resulting in less inhibitory action of the neurotransmitter. Finally, patients with psychiatric and/or personality disorders have an increased risk of paradoxical reactions to benzodiazepines.[5-7] In this group of patients, the highest risk is experienced by those with psychiatric histories of anger and aggressive behavior. The exact mechanism of paradoxical reaction development in these patients is unclear.[4]
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Post by slowmetabolizah on Jul 21, 2014 23:14:05 GMT
im not a doctor but this reminds me of something I came across before. if your liver is having trouble clearing/metabolising a drug it just swims around your body for much longer. taking more, if so, can be quite bad. a never ending high and a straight jacket probably! i believe some drugs are known for knocking out some of your liver enzymes in this way. or you may also be one of those who produce a weird metabolite instead of the one 95% of the population produce, due to your genes. sorry i dont know specifics. this stuff is fascinating I think!
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Post by carly31 on Jul 21, 2014 23:50:05 GMT
Ssri's made me totally insane. I was so high off them I was hallucinating and could not stop moving. I felt pretty mentally ill. I was paranoid that the ambulance was after me to section me. Medication induced hypomania they used antipsychotics to bring me back to earth. Snri's made me euphoric, happy, sleepy, hungry and a bit (Very) chubby. It was a nice feeling but I guess euphoria is probably not a good sign either.but it felt so good! I lost 3stone in about 2months once I was back to my normal hyper self. I do have gilberts syndrome. Wonder if that has anything to do with metabolising drugs. I get stoned just from being in the same room as my friend who smokes. I can't smoke that because it makes my ptsd flare up. Alcohol used to make me so anxious the day after. Co-codamol is too strong. Actually my mother is sensitive to medication too. The cancer drugs they gave her nearly killed her. She was super sensitive to them, they halved the recommended dose. Maybe it is genetic then. I'm a fine example of a rebel of the standard deviation!
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Post by contrarymary on Jul 22, 2014 14:18:05 GMT
my daughter also has a paradoxical reaction to diazepam, exactly like mine, as we discovered when she had surgery last year. she doesn't stop talking, is completely out there with her emotions and moves around loads, all the while feeling very relaxed and uninhibited. she said that she felt how i normally look i had a small trial of benzos again about a year ago - i had massive tics almost constantly, verbally and physically, but didn't mind at all
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Post by carly31 on Jul 23, 2014 23:58:31 GMT
i meant addiction as a physical thing - the brain/body quickly adjusts and has some sort of dysfunction without it - rather than a psychological addiction. (tho actually the interplay of the two can be pretty complicated, as i discovered when stopping smoking and the way my brain went haywire without nicotine... but that's another story) v best of luck with the exams carly31I think that those couple of days on diazepam turned me into the devil itself. Was getting well shitty with people and taking everything as a personal attack. Best off those bad boys I think!
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Post by Ramona on Dec 23, 2018 18:23:06 GMT
I have been on Valium about 4 to 6 weeks. Dr. Put me on it for restless legs ( they would hurt 12 hours every night. Pain gone never felt better. I’ve been brow beaten all my life, all that’s gone & I just feel really good.
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blach98
Member's not posted much yet
Posts: 16
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Post by blach98 on Dec 26, 2018 2:54:58 GMT
that's so weird, i'm the exact same and benzos like valium make me hyper.
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