cc
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Post by cc on Nov 3, 2013 13:03:17 GMT
Thanks JJ, that makes sense. I think i took the second dose too soon because I was still feeling good when i took it. I took my first dose today at 11am and its still working which is just as well because I have loads of things to get done today. I am going to wait for it to wear off before the next dose. It is a fine balance isn't it. My psych says i need to listen to my body more. I just panic about rebounding.
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Post by JJ on Nov 3, 2013 13:17:02 GMT
Actually I've found the opposite re listening to my body! When the meds are starting to wear off, but still an hour and half til the next dose (4 hrs), my body tells me I need another tablet - but if I take it then, I get the feelings you described or similar, which indicate I've taken too much.... I know now to ignore that feeling and wait til I should otherwise I'll regret it later. Although the caveat with that is that I take my second dose slightly before the 4 hours (cos the first dose of the day seems to need a bit more or go more quickly). I think that's why long acting might be good - but the thought of getting it wrong and having to feel like that all day is just horrible for me. If you notice any slight things make a difference, do post them - I've not perfected it for myself yet - so all useful info
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cc
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Post by cc on Nov 3, 2013 14:55:47 GMT
Mmmm, its tricky isn't it. So I should be due by second dose now as I took the last one at just before 11am. Have a bit of tinnitus which is probably the dose wearing off and headache. Will eat and take dose 2, which means the second dose will be roughly five hours later. Would be great if the second dose was as good as the first one. Same thing happened on Friday - crappy feeling with second dose but then ok with third. Concerta sounds good....... I'm curious what dexedrine would be like, i've read that a lot of people find it smoother and its longer lasting as well.
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cc
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Post by cc on Nov 3, 2013 15:51:58 GMT
Ok, i'm into my second dose now and it feels really good. Much like the first one. The only thing i did differently with this second dose compared to all the other ones is that I took it half way through a big meal. I always take my first dose with breakfast or just after. Maybe food could be the difference but thank god no tinnitus, headache and sleepiness. I'd be surprised if a big meal could cause such a different reaction. I am able to focus my attention now although i am still as distracted as ever. The difference with MPH is i can refocus more easily. The biggest difference for me however is that my impulsivity has more or less gone which is amazing. I am a bit disappointed with the attentional stuff though.... What do you think?
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Post by odat on Nov 3, 2013 16:52:33 GMT
Mmmm, its tricky isn't it. So I should be due by second dose now as I took the last one at just before 11am. Have a bit of tinnitus which is probably the dose wearing off and headache. Will eat and take dose 2, which means the second dose will be roughly five hours later. Would be great if the second dose was as good as the first one. Same thing happened on Friday - crappy feeling with second dose but then ok with third. Concerta sounds good....... I'm curious what dexedrine would be like, i've read that a lot of people find it smoother and its longer lasting as well. Do you always take your medication with food? I find taking Ritalin to be more effective on an empty stomach. This may be one reason the morning meds work better. Btw, I agree with trying out a bigger dose in the mornings / smaller doses later.
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cc
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Post by cc on Nov 3, 2013 17:27:26 GMT
Hi Odat, I always take the first dose with breakfast, the second dose has been on an empty stomach and the second doses have been horrible. Tried my second dose today with food and no problem Not really sure yet as I am quite new to adhd meds.
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Post by JJ on Nov 4, 2013 22:48:54 GMT
I remember reading that mph is absorbed more quickly (? or more of it is absorbed or something positive anyway) with food.
I asked the GP and she said to take with food
Saying that, my morning dose is always best regardless of whether I've eaten or not, but the second and especially the third don't work as well unless I've eaten.
How did you get on today cc?
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cc
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Post by cc on Nov 5, 2013 16:50:32 GMT
Thanks jj, today I had first and second dose on empty stomach and it was good. In fact very good. I have been reading for work feeling so peaceful and undistracted. Still working out the food thing, half the patient info says with and half says without . I'll ask my Psych in two weeks time when I go again. Today feels great, bit anxious with morning dose but that's it. Don't know what happened to me last time when I had to go to bed exhausted and with a headache! I'll let you know what he says. Also the bigger doses Def work better for me.
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cc
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Post by cc on Nov 5, 2013 17:02:22 GMT
What's your dosing strategy jj? Is it just mph?
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cc
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Post by cc on Nov 5, 2013 17:04:10 GMT
I was interested in buproprion ages ago for depression before i was diagnosed with adhd but my gp said no. Only for smoking!
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Post by JJ on Nov 9, 2013 2:00:53 GMT
Sorry it's taken a while to reply - I've been having trouble with my meds. I'm taking buproprion for mood - and it is only licensed here for smoking - so has been prescribed off license. My GP wouldn't do that, only the psych would. I'm still getting used to the dosage ATM, it's done my head in so far, but today I'm feeling v slightly better - still need to wait another week or so before I have a verdict - I've got a thread on it, I'll post on there when I can. Xx
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Post by JJ on Nov 9, 2013 2:22:48 GMT
cc I meant to say that I read twice today that mph shouldn't be taken with a high fat meal as this stops it absorbing properly and what's left takes a couple of hours to have an effect. Said should have any high fat stuff at least an hour before or hour after taking the meds. Also said this re Dex It was an ok web site, but not properly ok like NICE or NHS - but was written by a dr....
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cc
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Post by cc on Nov 9, 2013 21:22:46 GMT
Oh that sounds rough with the buproprion. So far the MPH has had a much better effect on my mood than any anti depressant i've tried and their side effects have always been pretty rough for the first couple of weeks. So no fat and MPH, no citrus either apparently.
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Post by JJ on Nov 9, 2013 22:27:52 GMT
Oh yes - mph's mood lift was absolutely the best thing to come from the meds - but the bloody buproprion has sabotaged that for the time being....
Re the citrus - I'm 99% that's only relevant to Dex.... (And the article I read yday said no evidence citrus has an effect on mph, tho some said it made the outer coating break down more easily, which affects absorption )
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cc
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Post by cc on Nov 10, 2013 10:59:22 GMT
So why did you introduce the buproprion? Was it for an extra lift/motivation? What's your mood like? Is it very fluctuating or is it consistently low? The only thing I don't like about the MPH is sometimes it makes me feel a bit flat, however the mood lift is quite amazing to be honest. I am so much better with people now and hardly ever ruminate over past arguments or grievances. I don't really want to change mph because its neuroprotective compared to dex.
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Post by JJ on Nov 10, 2013 15:43:27 GMT
I took buproprion to counteract the mood drop caused by no nicotine. I don't want to derail this thread about it - I have a thread on it (buproprion and mph) - we should go there for that - I'm going to write on there soon anyway But, v interested to hear you say mph has a neuroprotective effect - can you elaborate / provide a link ? Xx
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cc
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Post by cc on Nov 10, 2013 16:28:09 GMT
Sure, MPH works primary by inhibiting the dopamine reuptake carrier. This has been shown in animal studies (i'm vegetarian so I hate animal studies) to have neuroprotective effects and perhaps even preventative of Parkinsons Disease. Its not uncommon for reuptake inhibitors to demonstrate neuroprotective properties. Fluoxetine for example has been researched for being neuroprotective against MDMA. Dex on the other hand is primarily a dopamine releasing drug and therefore not protective Here are some links, the second link is better. www.ncbi.nlm.nih.gov/pubmed/16736241www.ncbi.nlm.nih.gov/pmc/articles/PMC2701286/
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Post by JJ on Nov 10, 2013 21:05:08 GMT
Thanks for that I had a skim through - hurray if it turns out I'm getting a bit of protection from Parkinson's Disease
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Post by levellers on Jan 30, 2014 23:34:14 GMT
I would be interested to hear from anyone who has had a batch of Medikinet with a lack of active ingredient. My current batch appears to be lacking the most important chemicals!
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Post by random on Feb 6, 2014 11:06:20 GMT
Has anyone else reported high blood pressure on MPH. GP sent me for an ECG.
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mishmash
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Post by mishmash on May 29, 2014 10:30:58 GMT
It is interesting what people are saying about Medikinet. I've just taking ADHD medication and it is Medikinet Adult (it was prescribed in Germany, so might be a slightly different branding, but I think it is the slow release). I've been taking just 5mg and I've found that I've got a buzzing in my head. It is like a little bit of a beer buzz, which is a little disconcerting. It isn't too uncomfortable, but it doesn't feel like I thought it would. That is hardly the concentration I was expecting. Anyone have similar reactions to Medikinet? Or it is something that I'm feeling because it is the first time I've taken ADHD meds?
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Deleted
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Post by Deleted on May 29, 2014 10:48:59 GMT
5mg of methylphenidate is not going to have much of an impact on any adult - it's a baby dose and you're preparing your body to accept higher in small steps.
You should be feeling something but it's not going to be significant.
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Endymion
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Post by Endymion on Jul 21, 2014 7:19:16 GMT
I wonder if anyone has any advice on the problems with lack of appetitie and sleep caused by the drugs. I am quite a big bloke and on 3 x 30mg of Medikinet a day. It works wonders for me and has changed my life and losing some weight has been an added blessing, but I cannot go on losing weight and not eating well. I have started to drink nutrient shakes to try and supplement my diet, however, I would rather try and eat good wholesome food - but I simply just have no desire to eat most of the time.
I also do a lot of time in the gym and swimming most days, with a few rest days here and there during the week. I can get to sleep relatively easily, just cannot sleep for long - 2-3 hours max before I wake up and then hours before I can get back to sleep but then virtually time to get up again.
So, just wondering if anyone has any ideas on improving appetitie or sleeping?
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Post by MAS on Oct 17, 2014 22:44:13 GMT
I have been prescribed 50mg of ecquasym XL, recently the drugs have been giving me insane come downs, to the point that I feel insane depression and suicidal thoughts. I'm waiting to see specialist to change meds but can't get an appointment for another year as I'm 20 . Can anyone recommend a drug I can take, like Valium or something that will make me feel better... It's like the most insane depression and I just can't put up with it anymore! Thanks for your help
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Deleted
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Post by Deleted on Oct 18, 2014 0:46:38 GMT
Hi MAS
Tell your medic that you're having suicidal ideation (that's medic lingo for thoughts) and you should get an appointment on a priority basis. Basically read them what you wrote.
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Post by smogz101 on Dec 17, 2015 19:56:35 GMT
My meds have been upped from 2x5mg a day to 3x10mg instant release... Not a big breakfast person so take the first one after a banana and it works fine, main difference is how calm I am, impulsivity almost completely gone and feel like I have a few extra seconds to think calmly/process stuff!
Still not seeing a major difference in concentration but with improvements in other areas I can cope with this better!
However 2nd and 3rd doses don't work half as well! was wondering is this something to do with what I'm eating!? I've lost half a stone since starting meds as my appetite is non-existant, but I'm now making sure I get my calories in where I can! Does anyone on here have higher doses in the afternoon?
Also the 5mg were only lasting 2hours, the 10mg about 3 hours .... My metabolism must b pretty fast..
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Post by Swings&roundabouts on Jan 22, 2016 20:55:09 GMT
Hi everyone I'm really glad to find this site! I'm 40 year old english woman live in germany & diagnosed 2 weeks ago. Have been taking Medikinet adult 10mgs every morning for last 6 days & im not feeling good! I spend most of day feeling speedy & chaotic then crash in the evening & feel quite down. The psychiatrist did say I need to adjust dose & work out right dose etc but I have no idea how to do this. And can't seem to get an appointment with him. I tried taking 20mgs (in 2 doses) on one day but that just made me feel even more crazy! Is this normal? I would appreciate any feedback / advise .. Thank you xxx
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Post by Rubie do on Oct 24, 2016 18:17:55 GMT
Hi I'm just wondering if anyone can help me my 9 year old daughter has been diagnosed with adhd 3 years ago after trying lots of different meds she's now on equasym xl 30 mg she was on concerta before this. Her weight has decreased as she has no appetite wich happens to a lot of people on these meds but now her hair has become brittle thin has broken off she had lovely thick hair before also all her eyelashes have fallen out too this is breaking my heart to watch I'm not sure if it's a side affect of the meds or stress as we have been through a real tough time over the last 2 years with a nasty family on our St bullying us they even swore at my kids but they witnessed a lot she witnessed a 16 stone man come to my door and put his hands round my throat she was screaming he's got my mummy she was extremely traumatised by this so I don't know if it's stress I'm just wondering if anyone has had this side affect On this drug I'm at my witts end please help
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Post by JJ on Oct 25, 2016 3:40:49 GMT
This can be a side effect of stimulants as they're vasoconstrictors. However, both equasym and concerta are long acting methylphenidate - the only difference between them is the delivery system which releases the drug slowly - so I'd find it surprising if it was just due to equasym and ok on concerta (that's what I inferred from what you wrote).
Some people experiencing hair loss find it calms down after a bit, some people find that changing to instant release methylphenidate makes it better.
Hair loss doesn't affect a lot of people though - it's a recognised effect, but only some people find it. However, I've not heard of anyone saying their child has been affected (though this is an adult forum, so mainly adults asking about themselves), I've not heard of anyone saying their hair became brittle and was breaking, and no one has said their eye lashes came out.
It might be that it's nothing to do with the meds. I'd certainly pursue other avenues as well as finding out about ADHD meds. A friend of mine lost a lot of hair when she'd suffered a period of stress (it grew back after a few years btw). Ask your GP about referring her to a specialist about this.
The above notwithstanding, ADHD meds can be quite nuanced in the way they affect even an individual - so even though the same generic medication is used, sometimes it really does make a significant difference whether they're long acting or short acting, or what the delivery system is (which only differs in long acting meds) or even what the brand is.
there are other ADHD medications she could try - there is at least 1 other type of long acting methylphenidate, or 2-3 brands of instant.
Or there's elvanse, which is like a long acting dexamphetamine (the other stimulant) - it's a pro-drug, which changes to dexamphetamine once it's been swallowed. Or there's strattera.
Changing ADHD meds me especially if methylphenidate is working, isn't something to take lightly, as the new one might not work as well. Much better to look at changing the type / brand of the existing one if it is working.
I'm not a dr by the way and not writing in any medical capacity. I'm really sorry what's happening and I wish you luck xx
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Post by vagueandrandom on Oct 25, 2016 9:59:48 GMT
Regarding JJ s comment about the differences in generics . . I posted this yesterday linkI'm presuming you've taken your daughter to the GP. It could be caused by stress.
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